Sweden
Global Fin Swe Nor Den Ger Cze Svk Pol Hun USA
  • Logo
  • Produkter
  • Om oss
  • Nyheter
  • Kontakt
  • Hållbarhet
  • Instrument service
  • Aidian Connect
  • Aidian Academy
  • Antimicrobial resistance
Sök
Logo
  • Patientnära diagnostik
  • Mikrobiologi
  • Molekylär mikrobiologi
  • Molekylär onkologi
  • Hematologi
  • Hygienkontroll
  • RIA / Kollagener
  • COVID-19
  • Andra
Patientnära diagnostik
  • QuikRead go
  • QuikRead 101
  • Aidian LF
  • Nova Biomedical
  • SD BIOSENSOR STANDARD™ F
  • bioLytical Laboratories INSTI®
  • ACRO™ Biotech
  • microINR
  • Biosynex
  • Certest
  • Actim
  • Pulsar
  • GenSure
Läs mer
QuikRead go
  • QuikRead go Instrument
  • QuikRead go easy CRP
  • QuikRead go CRP
  • QuikRead go CRP+Hb
  • QuikRead go wrCRP
  • QuikRead go wrCRP+Hb
  • QuikRead go HbA1c
  • QuikRead go Strep A
  • QuikRead go iFOBT
  • QuikRead go tillbehör
QuikRead go
Mikrobiologi
  • Uricult
  • Uricult Vet
  • Cultura M
  • Reagena
  • MIKROGEN serologi
  • Meridian Immunoassays
  • Meridian Curian®
Läs mer
Molekylär mikrobiologi
  • ELITech Molecular Diagnostics
  • Meridian Revogene®
  • Meridian Alethia®
  • MIKROGEN molecular diagnostics
  • SD BIOSENSOR STANDARD™ M10
Läs mer
Molekylär onkologi
  • Nucleix – Bladder EpiCheck®
Läs mer
Hematologi
  • Norma Icon
Läs mer
Hygienkontroll
  • Easicult
  • Hygicult
  • Clean Card PRO
Läs mer
RIA / Kollagener
  • UniQ RIA
Läs mer
COVID-19
  • COVID-19-tester
Läs mer
Andra
  • Grifols Promonitor®
Läs mer
Logo
Stäng
  • Produkter
    • Patientnära diagnostik
      • QuikRead go
      • QuikRead 101
      • Aidian LF
      • Nova Biomedical
      • SD BIOSENSOR STANDARD™ F
      • bioLytical Laboratories INSTI®
      • ACRO™ Biotech
      • microINR
      • Biosynex
      • Certest
      • Actim
      • Pulsar
      • GenSure
    • Mikrobiologi
      • Uricult
      • Uricult Vet
      • Cultura M
      • Reagena
      • MIKROGEN serologi
      • Meridian Immunoassays
      • Meridian Curian®
    • Molekylär mikrobiologi
      • ELITech Molecular Diagnostics
      • Meridian Revogene®
      • Meridian Alethia®
      • MIKROGEN molecular diagnostics
      • SD BIOSENSOR STANDARD™ M10
    • Molekylär onkologi
      • Nucleix – Bladder EpiCheck®
    • Hematologi
      • Norma Icon
    • Hygienkontroll
      • Easicult
      • Hygicult
      • Clean Card PRO
    • RIA / Kollagener
      • UniQ RIA
    • COVID-19
      • COVID-19-tester
    • Andra
      • Grifols Promonitor®
  • Om oss
  • Nyheter
  • Kontakt
  • Hållbarhet
  • Instrument service
  • Aidian Connect
  • Aidian Academy
  • Antimicrobial resistance

Föreslagna ämnen

antibiotic resistance CRP point-of-care

Populära produkter

Meridian Curian® Campy

Meridian Curian® Campy

Biosynex COVID-19 Ag BSS snabbtest

Biosynex COVID-19 Ag BSS snabbtest

Real-Time PCR Test Menu

Real-Time PCR Test Menu

Senaste nyheter

Visa alla

Tripledemic - Aidian offers tools for SARS-CoV-2, influenza A&B and RSV diagnostics

26 januari 2023 | Nyheter, Produktnyheter

When time matters, rapid point of care testing can support treatment decisions

17 januari 2023 | Nyheter, Produktnyheter

Increase in invasive group A streptococcal (iGAS) infections reported in several countries

10 januari 2023 | Nyheter, Produktnyheter

  • Visa alla
  • Inga resultat
  • Loading...

Nyheter

Tripledemic - Aidian offers tools for SARS-CoV-2, influenza A&B and RSV diagnostics

26 januari 2023 | Nyheter, Produktnyheter

When time matters, rapid point of care testing can support treatment decisions

17 januari 2023 | Nyheter, Produktnyheter

Tillbaka till alla nyheter
8 september 2021
Nyheter,
AMR,
COVID-19

Antimicrobial resistance has accelerated during COVID-19

In the past decade, antimicrobial resistance (AMR) has been pointed out as an emerging global health threat. Now there are concerns that COVID-19 may have accelerated AMR due to increased use of antibiotics, although there is no scientific evidence that antibiotics would benefit in the treatment of COVID-19. Also, the increased number of hospital stays and invasive procedures in intensive care units (ICU) increased the risk for secondary bacterial infections that may require antibiotic therapy1. In ICU, ventilator associated pneumonia is a relatively common secondary infection, but patients also have urinary tract and bloodstream infections.

Antibiotics are commonly used in COVID-19 without confirmed secondary bacterial infection

At the beginning of the pandemic, antibiotics were widely used and prescribed especially for hospitalized COVID-19 patients often without an appropriate diagnosis of bacterial co-infection. As an example, in a multi-hospital cohort study in the USA, 57% of the 1705 patients received early empiric antibiotic treatment, of which only 3.5% had bacterial infection2. Another example from the USA is a study with almost 5000 participants demonstrating that during the first six months of the pandemic, 52% of the hospitalized COVID-19 patients had at least one antibiotic prescription and 36% multiple antibiotics. Up to 96% of these prescriptions were given empirically, without confirmation about the bacterial infection3. A review study evaluating the number of secondary infections in COVID-19 reported that secondary bacterial or fungal infections were in approximately 8% of the patients, but the antibiotics were prescribed for 72% of the patients4. In China, even up to 99% of the patients have received antibiotics without a diagnosed bacterial co-infection5.

CRP could aid in decreasing unnecessary antibiotic prescribing in COVID-19

Antimicrobial stewardship activities have slowly integrated into clinical guidelines that have started to recommend avoidance of antibiotics for mild and moderate COVID-19 unless there is clinical suspicion of secondary bacterial infection6,7. C-reactive protein (CRP) has been reported as a potential tool to guide antibiotic prescribing in secondary bacterial infections11. In COVID-19 patients, C-reactive protein levels are commonly slightly elevated between 20-50 mg/l8-10, whereas in hospitalized patients with secondary bacterial infection, CRP is significantly higher. A German study with 99 participants reported that patients admitted to the hospital, who develop a bacterial infection, had significantly higher CRP mean on admission (130 mg/l) and during hospital stay (mean highest CRP value 293 mg/l) compared to patients who did not have secondary infection 73 and 94 mg/l, respectively11. CRP had a sensitivity of 81% and a specificity of 76% for the detection of secondary bacterial infection, and the negative predictive value was 90% in patients with CRP < 172 mg/l. Therefore, CRP could be useful especially in ruling out bacterial coinfection and in decreasing unnecessary antibiotic prescribing.

References

  1. Cong W, Poudel AN, Alhusein N et al. Antimicrobial Use in COVID-19 Patients in the First Phase of the SARS-CoV-2 Pandemic: A Scoping Review. Antibiotics 2021; 10(6): 745.
  2. Vaughn VM, Gandhi TN, Petty LA et al. Empiric Antibacterial Therapy and Community-onset Bacterial Coinfection in Patients Hospitalized With Coronavirus Disease 2019 (COVID-19): A Multi-hospital Cohort Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021; 72(10): e533-e541.
  3. The PEW Charitable Trust. Could Efforts to Fight the Coronavirus Lead to Overuse of Antibiotics?, 2021.
  4. Rawson TM, Moore LSP, Zhu N et al. Bacterial and Fungal Coinfection in Individuals With Coronavirus: A Rapid Review To Support COVID-19 Antimicrobial Prescribing. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020; 71(9): 2459-2468.
  5. Cao J, Tu W-J, Cheng W et al. Clinical Features and Short-term Outcomes of 102 Patients with Coronavirus Disease 2019 in Wuhan, China. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020; 71(15): 748-755.
  6. National Institute for Health and Care Excellence (NICE). COVID-19 Rapid Guideline: Managing COVID-19: March 2021.
  7. World Health Organization. COVID-19 Clinical management - Living guidance, 2021.
  8. Chen N, Zhou M, Dong X et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet 2020; 395(10223): 507-513.
  9. Gao Y, Li T, Han M et al. Diagnostic utility of clinical laboratory data determinations for patients with the severe COVID-19. J Med Virol 2020; 92(7): 791-796.
  10. Mo P, Xing Y, Xiao Y et al. Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China. Clin Infect Dis 2020.
  11. Pink I, Raupach D, Fuge J et al. C-reactive protein and procalcitonin for antimicrobial stewardship in COVID-19. Infection 2021.
Share
Facebook
Twitter
E-post

Aidian Sweden AB

Råsta Strand väg 13C 169 79 Solna

Förfrågningar
info@aidian.se

Försäljning
order@aidian.se

08 623 04 00

Faktureringsadresser

E-faktura
(bara pdf-format) SE559186790701@xbs-salo.com

FO-nummer 559186-7907

  • Kontakt
  • Aidian Connect
  • Aidian Academy
  • Dataskydd
    • Integritetsskyddspolicy
    • Integritetsmeddelande
    • Cookiepolicy
    • Social Media Policy (in English)
    • Återkalla direktmarknadsföringstillståndet
  • Karriär
  • Hållbarhet
  • Produkter
    • QuikRead go
    • QuikRead 101
    • Aidian LF
    • Easicult
    • Hygicult
    • Clean Card PRO
    • Uricult
    • Uricult Vet
    • Cultura M
    • UniQ
    • Nova Biomedical
    • bioLytical Laboratories INSTI®
    • ACRO™ Biotech
    • microINR
    • Biosynex
    • Certest
    • Actim
    • Pulsar
    • GenSure
    • SD BIOSENSOR STANDARD™ F
    • Reagena
    • MIKROGEN serologi
    • Meridian Immunoassays
    • Meridian Curian®
    • ELITech Molecular Diagnostics
    • Meridian Revogene®
    • Meridian Alethia®
    • MIKROGEN molecular diagnostics
    • SD BIOSENSOR STANDARD™ M10
    • Nucleix
    • Norma Icon
    • Grifols Promonitor®
    • COVID-19-tester
Copyright © 2023 Aidian

Denna webbplats använder kakor

Vi använder kakor för att kunna rikta relevant innehåll och annonser till dig, för att kunna analysera trafiken och för att vi ska kunna säkerställa att tjänsterna fungerar som de ska.

Redigera inställningar

Nödvändiga (Obligatorisk)

Kakor som krävs för att webbplatsen skall fungera normalt. Detta innehåller kakor som används för inloggning samt för CSRF säkerhet. Vänligen notera att webbplatsens egna kakor inte samlar personlig eller känslig information. IP-adresser samlas inte. Informationen som samlas skickas inte ut åt tredje parter.
— CraftSessionId
Provider: denna sida
Expiration: Session
Description: Webbplatsen använder PHP sessioner för att upprätthålla sessioner. Systemet nämner cookien i fråga “CraftSessionId”. Denna cookie upphör så fort sessionen avslutas.
— *_identity
Provider: denna sida
Expiration: Beständig
Description: Då du loggar in i kontrollpanelen sätts en cookie som kontrollerar ditt inloggnings status. Namnet av cookien börjar med en lång slumpmässig text som följs av _identity. Cookien sparar endast nödvändig information för att upprätthålla en säker session, och hålls aktiv endast så länge som användaren är inloggad i systemet.
— *_username
Provider: denna sida
Expiration: Beständig
Description: Om du kryssar i "Håll mig inloggad" (Keep me logged in) under inloggnings processen, används denna cookie för att komma ihåg ditt användarnamn inför följande gång.
— CRAFT_CSRF_TOKEN
Provider: denna sida
Expiration: Session
Description: Skyddar oss och dig som en användare för CSRF attacker.

Statistik

Kakor som används för statistik hjälper oss förstå hur användarna använder och navigerar webbplatsen genom att samla och rapportera information anonymt.
— _ga
Provider: Google
Expiration: 2 år
Description: Identifikation av användare
— _gid
Provider: Google
Expiration: 24 timmar
Description: Kartläggning av användarens sidobesök
— _gat_UA-*
Provider: Google
Expiration: 10 minuter
Description: Begränsar mängden förfrågningar som sker mellan Googles reklam relaterade kakor

Marknadsföring

Marknadsförings kakor används för att spåra användarna genom webbplatsen. Meningen med dessa kakor är att kunna erbjuda användaren med mer relevant och personligt innehåll.
Göm inställningar